Introduction: Post-injection sciatic nerve palsy is a preventable iatrogenic peripheral nerve injury, commonly reported in pediatric populations following improper intramuscular injections in the gluteal region. It often leads to foot drop, sensory deficits, and gait abnormalities. Early physiotherapy intervention is essential to prevent long-term disability.

Methods: A 5-year-old male child presented with right lower limb weakness and abnormal gait following an intramuscular gluteal injection. Clinical examination and nerve conduction studies confirmed sciatic nerve palsy. A structured 12-week physiotherapy rehabilitation program focusing on pain control, muscle re-education, strengthening, gait training, and functional activities was implemented.

Results: Significant improvements were observed in muscle strength, gait pattern, and functional mobility. The child progressed from ankle-foot orthosis–assisted ambulation to independent walking with near-normal gait.