In our research we proved that the surgical modality is a suitable method for Carpel Tunnel Syndrome (CTS) as compare with a local injection in 300 cases-prospective study. About (150 cases) were treated by surgical release compared to local injection method that represented by the use of (Xylocaine plus steroid triamcinolone 40 mg) with samples were taken from AL-Husain medical city at the period (from July 2015 to January 2023). only two cases developed to complex pain regional syndrome, two cases superficial skin infection in diabetic cases and only single case continue pain despite release, while injection cases group develop (90%) has pain relief, and (8%) has no improvement at all and go for surgical release.